People who are obese could be at a higher risk of developing a certain type of bowel cancer while exercise lowers the risk, a study suggests.
Researchers in the US analysed data from thousands of men and women
to determine if there was a link between weight, exercise and the risk
for CTNNB1-positive or CTNNB1-negative bowel, or colorectal cancer.
A higher body mass index (BMI) was linked to an increased risk of
CTNNB1-negative colorectal cancer, while physical activity was
associated with a lower risk.
Both BMI and physical activity had no effect on the risk for
CTNNB1-positive colorectal cancer, according to the research pubished in
the journal Cancer Research.
Dr. Shuji Ogino, an associate professor of pathology at Dana-Farber
Cancer Institute and an associate professor in the department of
epidemiology at Harvard School of Public Health, said the results
provided further evidence for a causal role of obesity and a physically
inactive lifestyle in this specific type of bowel cancer.
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